Request PDF on ResearchGate | HgEDTA complex inhibits GTP interactions with the E-site of brain beta-tubulin | We have found that EDTA and EGTA complexes of Hg2+, which conventional wisdom has assumed are biologically inert, are potentially injurious to the neuronal cytoskeleton. Tubulin, a major protein component of the neuronal cytoskeleton, is the target of multiple toxicants,...