Henry Louis Gehrig played 17 seasons for the New York Yankees and was know as the "Iron Horse". He was the first MLB player to have his jersey retired. He suffered from the incurable disease, ALS, or also know later as Lou Gehrig's disease.
April 1939 - New York Yankees Lou Gehrig leaps over a bat held by Joe DiMaggio during spring training. Lou Gehrig played his last game on this day with the Yankees. He had previously played in consecutive games. (Sporting News Archives)
Neuraltus Pharmaceuticals Inc. will take its experimental Lou Gehrig’s disease drug into Phase III next year, representing a big move for the small Palo Alto company and a big victory for patients who fought to enroll an important mid-stage.