Burzynski Clinic | Advanced Integrative Cancer Treatment | Houston, Texas
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Gene Therapy Cures Color-Blind Monkeys
After receiving injections of genes that produce color-detecting proteins, two color-blind monkeys have seen red and green for the first time. Except in its extreme forms, color blindness isn’t a debilitating condition, but it’s a convenient stand-in for other types of blindness that might be treated with gene therapy. The monkey success raises the possibility \\[…\\]
This patient was diagnosed with a therapy-related acute myeloid leukemia, likely related to prior treatment with topoisomerase II inhibitors. The morphology is usually monocytic or myelomonocytic (as in this case), and the cytogenetic abnormalities frequently consist of 11q23 translocations involving the MLL gene.
CHIC2 on 4q12: Myeloid and lymphoid neoplasms with PDGFRA rearrangement constitute a new category in the 2008 WHO classification and are commonly associated with a FIP1L1-PDGFRA rearrangement, formed as a result of a cryptic deletion at 4q12. This deletion can be detected by fluorescence in situ hybridization using a probe for the CHIC2 gene. The recognition of this entity and its differential diagnosis from hypereosinophilic syndrome is important, because patients are responsive to…
Scientists are looking into a new technique for the fight against AIDS...and yes, it involves glow-in-the-dark cats! Two genes are inserted into feline eggs before fertilization, one being the jellyfish gene that causes cats to glow ("tracking purposes.") The other is a rhesus macaque gene that blocks cell infection by feline immunodeficiency virus, which provides insight into how gene therapy can treat the virus affecting humans. The macaque restriction factor, TRIMCyp, blocks FIV by…
Gene therapy beneficial but not permanent in serious immune disorder
Early trials in patients with chronic granulomatous disorder (x-CGD), a recessive X-linked condition that affects the immune system, have shown signs of success following the use of gene therapy. The observed boost in immunity of those undergoing treatment was only temporary, however, and the faulty gene causing x-CGD was not corrected permanently....